Memokath 051 Ureter stent for ureteric obstruction
Comments from the NICE committee in brief
1 Recommendations
1.1 Memokath 051 Ureter stent is recommended as an option to manage ureteric obstruction in adults with:
- malignant ureteric obstruction and anticipated medium- or long-term survival adjunctive therapy
- benign ureteric obstruction who cannot have or do not want reconstructive surgery
- any type of ureteric obstruction, and they cannot have or do not want a double-J stent, or when repeat procedures are particularly high risk.
1.2 Data should be collected prospectively on ureteric stent procedures, including details of patient selection, choice of stent placement procedure and stent used, and adverse events such as stent migration and encrustation rates.
The conclusion can be read in its full length on the NICE website.
Why the committee made these recommendations
NICE originally recommended Memokath 051 for ureteric obstructions for selected people.
New clinical evidence from retrospective studies suggest that Memokath 051 relieves ureteric obstruction as well as other stents.
For people with malignant ureteric obstruction, Memokath 051 may have advantages over some other treatments because it is less invasive procedure than nephrostomy, with no need for hospital stay, and fewer stent replacements needed compared with other stents.
Clinical expert also felt that it was important to have Memokath 051 as an option for other people, for example people who cannot have or do not want reconstructive surgery or a double-J stent, or when repeat procedures are particularly high risk.
The cost modelling suggests Memokath 051 is likely to be cost saving compared with other stents. This is because it may not need to be replaced as often as other stents. But the cost savings are not certain because there’s not enough good quality evidence.
There is enough clinical evidence to continue recommending Memokath 051 for selected adults with ureteric obstruction. But prospective data is still needed to be certain about the cost savings of using it, compared with other stents.
What is NICE?
NICE (National Institute for Health and Care Excellence) is an executive non-departmental public body of the Department of Health in UK serving the NHS (National Health Service) with evidence-based guidance within e.g. the use of technologies or clinical practices to improve health and social care. Through its rigorous clinical and health-economic assessment processes NICE is considered an international authority within health and social care guidance and plays an important role in influencing what technologies and clinical practices are used in the health care system in, as well as outside the UK.
For more information about NICE and its evaluation process please visit their official website.